A four-point gap between the visitors here and safety remains, despite victory over Crystal Palace.
Everton will be desperate for a reaction after being soundly beaten by Wolves last time out.
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While the added motivation of closing in on both Watford and West Ham before both face each other on Friday.
Here are the predicted line-ups for the game at Goodison Park.
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When is it and what time is kick-off?
The match will begin at 6pm on Thursday 16 July at Goodison Park.
How can I watch it online and on TV?
The match will be broadcast live on Sky Sports Action, Sky Sports Main Event and Sky Sports Ultra HD, and Sky subscribers can also stream the game on the Sky Go app.
If you’re not a Sky customer, you can grab a NOWTV Day Pass here to watch without a subscription.
What is the team news?
Jean-Philippe Gbamin (Achilles) and Fabian Delph (muscle) are set to remain on the sidelines. Yerry Mina’s thigh problem, which forced him off against Wolves means he is a big doubt here. Mason Holgate (shin) and Andre Gomes (knock) should recover in time to start here.
Kortney Hause (groin) pulled up in the warm-up against Palace, Neil Taylor suffered a knock after 36 minutes, while Bjorn Engels (Achilles) is a long-term absentee.
Everton XI: Pickford; Coleman, Keane, Holgate, Digne; Walcott, Sigurdsson, Gomes, Gordon; Calvert-Lewin, Richarlison
Aston Villa XI: Reina; Elmohamady, Konsa, Mings, Targett; McGinn, Douglas, Hourihane; Trezeguet, Samatta, Grealish
What are the odds?
Aston Villa: 13/5
The win over Palace will have done wonders for Villa, but the pressure remains fully on with four points separating them from safety. We’ll go with Dean Smith’s side to grind out a precious win, due to the extra motivation, setting up a gripping end to the relegation battle. 1-2.