It’s a crunch game at the bottom, with a win for either side almost certainly guaranteeing them survival.
The other side will head into the last two games knowing they still need a result to avoid the drop.
Sharing the full story, not just the headlines
Both teams won their last game and are level on 34 points ahead of kick-off.
Here’s all you need to know before the game.
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When is it and what time is kick-off?
The match will begin at 8pm on Friday 17 July at London Stadium.
How can I watch it online and on TV?
The match will be broadcast live on Sky Sports Premier League, Sky Sports Main Event and Sky Sports Ultra HD, and Sky subscribers can also stream the game on the Sky Go app.
If you’re not a Sky customer, you can grab a NOWTV Day Pass here to watch without a subscription.
What is the team news?
West Ham are missing attacking midfield duo Felipe Anderson and Robert Snodgrass, but are otherwise looking at a clean bill of health.
Watford are similarly not affected by any new injuries. Gerard Deulofeu, Daryl Janmaat and Isaac Success are all longer-term absentees from the team sheet.
West Ham: Fabianski; Fredericks, Diop, Ogbonna, Cresswell; Noble, Rice, Soucek; Bowen, Yarmolenko, Antonio.
Watford: Foster; Femenia, Dawson, Kabasele, Masina; Hughes, Capoue; Sarr, Doucoure, Welbeck; Deeney.
What are the odds?
West Ham: 10/7