The sacking of Nigel Pearson is still surrounded in mystery, with the Hornets still well-placed to beat the drop.
But defeat to Pep Guardiola’s side will open the door for Aston Villa and Bournemouth – depending on the severity of the loss.
Sharing the full story, not just the headlines
Goal difference could be the friend of Hayden Mullins as he steps in on a short-term basis to try finish the job Pearson started.
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The match kicks off at 18:00, Tuesday 21 June at Vicarage Road.
The game will be available to watch live on Sky One, Sky Sports Premier League, Sky Sports Main Event, Sky Sports Ultra HD and Pick. Coverage starts at 17:30.
If you’re not a Sky customer you can grab a NOWTV Day Pass here to watch without a subscription.
Gerard Deulofeu (knee), Isaac Success (Achilles) and Daryl Janmaat (knee) are all out. Deeney has had knee problems for a while, but he will likely play through the pain here.
Oleksandr Zinchenko, Joao Cancelo, John Stones and Nicolas Otamendi could all be set for run-outs if Guardiola rotates his squad, with Kyle Walker, Benjamin Mendy and Aymeric Laporte due a rest. While Gabriel Jesus could be handed a breather too, having started six games in a row in all competitions.
Watford XI: Foster; Mariappa, Kabasele, Dawson, Femenia; Hughes, Chalobah; Sarr, Doucoure, Welbeck; Deeney
Man City XI: Ederson; Walker, Stones, Laporte, Zinchenko; De Bruyne, Rodri, Silva; Sterling, Bernardo, Foden
The Hornets are in disarray and City will be fuelled by the hurt of losing the FA Cup semi-final last weekend, it has to be an away win here and more uncertainty at Vicarage Road heading into the final round of fixtures this weekend. 1-3.